TargetMine loads gene information from NCBI Gene. Read more

Query for genes:

• Gene(s)    Compound(s)
• Gene    Pathway
• Gene list    Compounds that target hub or bottleneck genes
• Gene + GO term name    Gene with the GO term name.
• Gene(s)    Integrated Pathway clusters
• Gene(s)    PPI Network properties (Bottleneck and Hub)
• Gene(s)    Expressed tissues (Barcode 3.0)
• Gene    Proteins.

More queries

TargetMine loads protein information from UniProt. Read more

Query for proteins:

• Protein(s)    Compound(s)
• Protein    Pathway
• Gene    Proteins.
• Protein(s)    Compound Group(s)
• Protein    All Protein Domains
• Protein(s)    PDB entries
• Type of UniProt Feature    Proteins
• Protein(s)    Gene(s)

More queries

TargetMine loads protein domain annotation from InterPro. Read more

Query for domain:

• Protein    All Protein Domains
• Protein Domain    Genes
• Protein    Protein Domains in the specified database
• Protein Domain    Proteins

More queries

TargetMine loads protein structure data including PDB, SCOP and CATH. Read more

Query for structure:

• Protein(s)    PDB entries
• Gene(s)    Protein(s)    Gene3D CATH classification annotations
• CATH classification    Proteins
• Enzyme(s)    PDB entries
• Protein(s)    Gene3D CATH classification annotations
• Protein    Protein structures co-crystalized with DNA
• ProteinStructure    Protein(s)
• Protein    PDBCompound    ChEMBL Activities

More queries

TargetMine loads physical interactions from BioGRID and iRefindex. Read more

Query for interactions:

• Gene(s)    Upstream transcription factors
• Transcription factor(s)    Downstream targets
• Gene(s)    PPI Network properties (Bottleneck and Hub)
• miRNA    All target genes
• Gene list    Species specific BIOGRID and iRefIndex PHYSICAL Interactions
• Gene(s)    High confidence direct physical (HCDP) PPIs
• miRNA    Functional targeting genes
• PPI for Gene A    Gene X    Gene B

More queries

TargetMine loads pathway data from KEGG, Reactome and NCI pathway. Read more

Query for pathways:

• Gene    Pathway
• Protein    Pathway
• Gene(s)    Integrated Pathway clusters
• Enzyme    Pathway
• EFO    Related Pathways

More queries

The compound data in TargetMine comes from several data sources, including ChEMBL, PubChem, and KEGG. Read more

Query for compounds:

• Gene(s)    Compound(s)
• Compound(s)    Target proteins with bioactivities
• Gene(s)    Diseases    Compound with 3D structure
• Protein(s)    Compound Group(s)
• ATC Code    Drug Compound(s)
• ChEMBL compound + Protein    Activities
• PubChem Compound    Target Proteins
• Protein    Compounds    Assay

More queries